KDM5A-IN-1 is primarily used in research settings to study the role of KDM5A, a histone demethylase, in various biological processes. It is a potent inhibitor of KDM5A, which is involved in the regulation of gene expression by modifying histone proteins. Researchers utilize this compound to investigate its potential in cancer therapy, as KDM5A is often associated with tumor progression and drug resistance. By inhibiting KDM5A, it may help reactivate silenced tumor suppressor genes, making it a promising candidate for epigenetic-based cancer treatments. Additionally, it is used to explore its effects on cellular differentiation, stem cell maintenance, and other epigenetic mechanisms.