IOX1 is primarily utilized in biochemical research as a potent and selective inhibitor of the Jumonji domain-containing histone demethylases, particularly KDM2/7. Its application is significant in the study of epigenetic regulation, where it helps to understand the role of histone demethylation in gene expression and cellular processes. Researchers employ IOX1 to investigate its effects on chromatin structure and function, which can provide insights into various diseases, including cancer, where epigenetic dysregulation is often observed. Additionally, IOX1 is used in the development of potential therapeutic strategies targeting epigenetic modifications, offering a pathway for novel treatments in oncology and other fields.