MG149 is primarily known for its role as an inhibitor of histone acetyltransferases (HATs), particularly the MYST family of HATs. This property makes it a valuable tool in research focused on understanding epigenetic regulation and gene expression. By inhibiting HAT activity, MG149 helps scientists study the impact of histone acetylation on various cellular processes, including DNA repair, transcription, and cell cycle control. Its application extends to cancer research, where it is used to explore the role of epigenetic modifications in tumorigenesis and to evaluate potential therapeutic strategies targeting epigenetic mechanisms. Additionally, MG149 is utilized in studies investigating the relationship between histone acetylation and other diseases, such as neurodegenerative disorders, providing insights into potential treatment avenues.