Used as a staining agent in histological techniques to visualize specific tissue structures, particularly in nerve tissues and reticulum fibers. Enhances contrast under light microscopy by selectively binding to proteins, allowing clear differentiation of cellular components. Commonly applied in silver impregnation methods like Bielschowsky’s stain for neurofibrils and reticulin staining in liver and spleen tissues. Provides high-resolution imaging of fine structural details due to strong signal intensity and specificity.