Used in histopathology for nuclear staining in tissue sections, this modified hematoxylin solution provides sharp contrast between cell nuclei and cytoplasm, enhancing microscopic evaluation. It is particularly effective in routine tissue examination and helps in identifying nuclear abnormalities such as hyperchromasia, pleomorphism, and increased mitotic activity. The modification improves staining consistency and reduces background precipitation, making it suitable for automated staining platforms. Commonly used in diagnostic labs for cancer detection, research studies, and educational purposes where clear nuclear detail is essential.