Roxatidine ethanedioate is primarily used in the treatment of gastrointestinal disorders, particularly those involving excessive stomach acid production. It is effective in managing conditions such as peptic ulcers, gastritis, and gastroesophageal reflux disease (GERD). By inhibiting histamine H2 receptors in the stomach lining, it reduces acid secretion, providing relief from symptoms like heartburn, indigestion, and stomach pain. Additionally, it is sometimes prescribed to prevent stress ulcers in critically ill patients. Its therapeutic benefits make it a valuable option for improving digestive health and enhancing patient comfort.