Azatadine dimaleate is primarily used as an antihistamine to treat symptoms associated with allergic conditions. It effectively alleviates symptoms such as sneezing, runny nose, itching, and watery eyes caused by hay fever or other upper respiratory allergies. Additionally, it is used to manage skin reactions like hives or itching due to chronic urticaria. Its sedative properties also make it useful in reducing nighttime allergy symptoms, aiding in better sleep for individuals suffering from severe allergic reactions. In some cases, it may be combined with other medications to provide relief from cold symptoms, though its primary role remains in managing allergic responses.