Cyclizine 2HCl is primarily used as an antihistamine to prevent and treat nausea, vomiting, and dizziness associated with motion sickness. It is also effective in managing symptoms of vertigo and inner ear disorders. In some cases, it is utilized to alleviate nausea and vomiting caused by certain medical treatments, such as chemotherapy or post-operative recovery. Additionally, Cyclizine 2HCl may be prescribed for its sedative effects to help patients with anxiety or insomnia. Its ability to block histamine receptors in the brain makes it a valuable option for controlling symptoms related to allergic reactions or histamine-induced conditions.