5-(Dimethylphosphoryl)picolinonitrile
97%
Reagent
Code: #178541
CAS Number
2551114-38-4
blur_circular Chemical Specifications
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Molecular Information
Weight
180.14 g/mol
Formula
C₈H₉N₂OP
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Storage & Handling
Storage
2-8°C, drying away from light
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its phosphine oxide group enhances binding selectivity to certain enzyme active sites, improving drug efficacy. Also employed in agrochemicals as a building block for novel pesticides due to its stability and reactivity in cross-coupling reactions. Serves as a ligand precursor in catalysis, especially in palladium-catalyzed transformations, supporting efficient carbon-heteroatom bond formation in fine chemical manufacturing.
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