4-(4-(4-(Trifluoromethoxy)phenoxy)piperidin-1-yl)phenol
≥95%
Reagent
Code: #244565
CAS Number
681482-81-5
blur_circular Chemical Specifications
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Molecular Information
Weight
353.34 g/mol
Formula
C₁₈H₁₈F₃NO₃
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Registry Numbers
MDL Number
MFCD16170437
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of selective estrogen receptor modulators (SERMs). It contributes to the structural framework that enables modulation of estrogen receptors, making it valuable in treatments for hormone-related conditions such as breast cancer and osteoporosis. Its fluorinated aromatic system enhances metabolic stability and binding affinity, which improves the efficacy and pharmacokinetic profile of the final drug compounds. Also employed in research settings for designing new bioactive molecules due to its favorable physicochemical properties and ability to cross cell membranes.
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