Tert-Butyl 4-(2-(4-(1-Benzyl-1H-Benzo[D]Imidazol-2-Yl)Phenoxy)-1-(2-Phenyl-1H-Benzo[D]Imidazol-1-Yl)Ethyl)Piperidine-1-Carboxylate
97%
Reagent
Code: #243745
CAS Number
1440754-07-3
blur_circular Chemical Specifications
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Molecular Information
Weight
703.87 g/mol
Formula
C₄₅H₄₅N₅O₃
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Storage & Handling
Storage
Room temperature
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of potent histamine H3 receptor antagonists. Its structure supports blood-brain barrier penetration, making it valuable in developing treatments for central nervous system disorders such as Alzheimer's disease, schizophrenia, and attention deficit hyperactivity disorder (ADHD). The compound's design allows for high selectivity and binding affinity to the H3 receptor, improving therapeutic efficacy while minimizing off-target effects. It is also employed in structure-activity relationship (SAR) studies to optimize pharmacokinetic properties in new drug candidates.
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