(2,3,6-Trifluorophenyl)hydrazine hydrochloride
98%
Reagent
Code: #243452
CAS Number
2137836-61-2
blur_circular Chemical Specifications
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Molecular Information
Weight
198.57 g/mol
Formula
C₆H₆ClF₃N₂
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used primarily as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals. Its trifluorinated aromatic structure enhances metabolic stability and bioavailability in drug candidates. Commonly employed in the preparation of heterocyclic compounds such as indoles and pyrazoles through cyclization reactions. Also utilized in medicinal chemistry research for developing kinase inhibitors and CNS-active agents due to the electron-withdrawing effect of fluorine atoms improving target binding and lipophilicity. Suitable for use in hydrazone formation and as a building block in combinatorial chemistry.
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