8-(Trifluoromethyl)quinolin-2-amine
≥95%
Reagent
Code: #242926
CAS Number
1092304-80-7
blur_circular Chemical Specifications
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Molecular Information
Weight
212.17 g/mol
Formula
C₁₀H₇F₃N₂
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Registry Numbers
MDL Number
MFCD11108677
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Physical Properties
Boiling Point
306.6±37.0 °C at 760 mmHg
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Storage & Handling
Storage
2-8°C, protected from light, dry, sealed
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in antimalarial drugs due to its quinoline backbone which shows biological activity against Plasmodium species. Also employed in the development of kinase inhibitors for cancer therapy, where the trifluoromethyl group enhances metabolic stability and binding affinity. Its amine functionality allows for easy derivatization, making it valuable in medicinal chemistry for creating compound libraries in drug discovery. Additionally, it serves as a ligand in catalytic systems for asymmetric synthesis, supporting the production of chiral molecules in fine chemicals and agrochemicals.
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