tert-butyl 4-hydroxy-4-(thiophen-2-yl)piperidine-1-carboxylate
98%
Reagent
Code: #242785
CAS Number
630119-99-2
blur_circular Chemical Specifications
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Molecular Information
Weight
283.39 g/mol
Formula
C₁₄H₂₁NO₃S
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of central nervous system (CNS) agents. Its piperidine core with a hydroxy and thiophene substituent makes it valuable in medicinal chemistry for constructing bioactive molecules. The tert-butyl carbamate (Boc) group protects the nitrogen during peptide or heterocyclic synthesis, allowing selective reactions at other sites. It is employed in research settings to design ligands for neurological receptors, including those targeted in treatments for depression, anxiety, and neurodegenerative diseases. Also utilized in creating novel analogs for structure-activity relationship (SAR) studies due to its stereochemical and electronic properties.
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