Tert-butyl trans-3-fluoro-4-hydroxypiperidine-1-carboxylate
97%
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description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of central nervous system (CNS) drugs. Its structural features, including the fluorinated piperidine ring and free hydroxyl group at the 4-position, make it valuable for constructing bioactive molecules with improved metabolic stability and blood-brain barrier penetration. The tert-butyl carbamate (Boc) group protects the piperidine nitrogen, allowing for selective functionalization during multi-step syntheses. Commonly employed in the preparation of selective receptor modulators, especially for neurological targets such as serotonin and dopamine receptors, enabling efficient route design in medicinal chemistry.
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