trans-1-(tert-butoxycarbonyl)-4-(3,4-difluorophenyl)pyrrolidine-3-carboxylic acid
98%
Reagent
Code: #241929
CAS Number
2227756-36-5
blur_circular Chemical Specifications
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Molecular Information
Weight
327.33 g/mol
Formula
C₁₆H₁₉F₂NO₄
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Storage & Handling
Storage
2-8℃
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors and central nervous system (CNS) active compounds. Its structural features enable selective interactions with biological targets, making it valuable in drug discovery programs focused on inflammation, neurological disorders, and oncology. The tert-butoxycarbonyl (Boc) protecting group allows for controlled reactivity during multi-step syntheses, facilitating peptide coupling and heterocycle formation. Its difluorophenyl moiety contributes to enhanced metabolic stability and membrane permeability, which are critical for oral bioavailability in final drug candidates.
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