Trans-(1-benzyl-4-(2-fluoro-5-(trifluoromethyl)phenyl)pyrrolidin-3-yl)methanol
98%
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Used in pharmaceutical research as a key intermediate in the synthesis of biologically active compounds, particularly in the development of central nervous system agents. Its structural features make it valuable for optimizing metabolic stability and receptor binding affinity in drug candidates. Commonly employed in the design of serotonin and dopamine modulators due to its chiral pyrrolidine core and fluorinated aromatic group, which enhance blood-brain barrier penetration. Also utilized in structure-activity relationship (SAR) studies to improve potency and selectivity of neuroactive drugs.
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