1-(2,2,2-Trifluoroethyl)piperazine dihydrochloride

95%

Reagent Code: #240988
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CAS Number 13349-91-2

science Other reagents with same CAS 13349-91-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 241.09 g/mol
Formula C₆H₁₃Cl₂F₃N₂
badge Registry Numbers
MDL Number MFCD08261052
thermostat Physical Properties
Boiling Point 233.7°C
inventory_2 Storage & Handling
Storage Room temperature, dry

description Product Description

Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of central nervous system (CNS) agents. It serves as a building block for bioactive molecules due to its ability to enhance metabolic stability and improve blood-brain barrier penetration. Commonly employed in the preparation of receptor agonists and antagonists, especially targeting serotonin, dopamine, and histamine receptors. Its trifluoroethyl group contributes to increased lipophilicity and resistance to enzymatic degradation, making it valuable in medicinal chemistry for optimizing drug candidates. Also utilized in research settings for structure-activity relationship (SAR) studies.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿2,450.00
inventory 5g
10-20 days ฿10,310.00
inventory 25g
10-20 days ฿50,930.00

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1-(2,2,2-Trifluoroethyl)piperazine dihydrochloride
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Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of central nervous system (CNS) agents. It serves as a building block for bioactive molecules due to its ability to enhance metabolic stability and improve blood-brain barrier penetration. Commonly employed in the preparation of receptor agonists and antagonists, especially targeting serotonin, dopamine, and histamine receptors. Its trifluoroethyl group contributes to increased lipophilicity and resistance to enzymatic degradation, making it valuable in medicinal chemistry for optimizing drug candidates. Also utilized in research settings for structure-activity relationship (SAR) studies.
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