8-(Trifluoromethyl)quinoline-5-carbonitrile
95%
Reagent
Code: #238400
CAS Number
2922283-53-0
science Other reagents with same CAS 2922283-53-0
blur_circular Chemical Specifications
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Molecular Information
Weight
222.17 g/mol
Formula
C₁₁H₅F₃N₂
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its structure supports binding to enzyme active sites, enhancing selectivity and potency. Also employed in agrochemicals to improve metabolic stability and bioavailability. The electron-withdrawing trifluoromethyl and nitrile groups contribute to enhanced lipophilicity and resistance to degradation, making it valuable in designing bioactive molecules. Additionally, it serves as a building block in materials science for creating fluorescent probes and optoelectronic materials due to its rigid aromatic framework and electronic properties.
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