8-(Trifluoromethyl)quinoline-5-carbonitrile

95%

Reagent Code: #238400
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CAS Number 2922283-53-0

science Other reagents with same CAS 2922283-53-0

blur_circular Chemical Specifications

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Weight 222.17 g/mol
Formula C₁₁H₅F₃N₂
inventory_2 Storage & Handling
Storage Room temperature, seal, dry

description Product Description

Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its structure supports binding to enzyme active sites, enhancing selectivity and potency. Also employed in agrochemicals to improve metabolic stability and bioavailability. The electron-withdrawing trifluoromethyl and nitrile groups contribute to enhanced lipophilicity and resistance to degradation, making it valuable in designing bioactive molecules. Additionally, it serves as a building block in materials science for creating fluorescent probes and optoelectronic materials due to its rigid aromatic framework and electronic properties.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿32,250.00
inventory 1g
10-20 days ฿147,910.00
inventory 250mg
10-20 days ฿54,790.00

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8-(Trifluoromethyl)quinoline-5-carbonitrile
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Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its structure supports binding to enzyme active sites, enhancing selectivity and potency. Also employed in agrochemicals to improve metabolic stability and bioavailability. The electron-withdrawing trifluoromethyl and nitrile groups contribute to enhanced lipophilicity and resistance to degradation, making it valuable in designing bioactive molecules. Additionally, it serves as a building block in materials science for creating fluorescent probes and optoelectronic materials due to its rigid aromatic framework and electronic properties.
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