(S)-3-(Toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid benzyl ester

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Reagent Code: #236423
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CAS Number 158654-83-2

science Other reagents with same CAS 158654-83-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 375.439 g/mol
Formula C₁₉H₂₁NO₅S
thermostat Physical Properties
Boiling Point 537.9±50.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.33±0.1 g/cm3(Predicted)
Storage Room temperature, seal, dry

description Product Description

Used as a chiral intermediate in the synthesis of pharmaceutical compounds, particularly in the development of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity. Its protected alcohol and amine functionalities make it suitable for sequential coupling reactions in multi-step organic syntheses. Commonly employed in the preparation of protease inhibitors and other bioactive molecules where stereochemistry plays a critical role in biological activity. The tosylate group acts as a leaving group, enabling nucleophilic substitution to introduce various side chains, while the benzyl carbamate (Cbz) group protects the nitrogen and can be removed under mild conditions without affecting other functional groups. Widely applied in medicinal chemistry for constructing complex nitrogen-containing heterocycles.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿10,040.00
inventory 1g
10-20 days ฿38,230.00
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(S)-3-(Toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid benzyl ester
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Used as a chiral intermediate in the synthesis of pharmaceutical compounds, particularly in the development of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity. Its protected alcohol and amine functionalities make it suitable for sequential coupling reactions in multi-step organic syntheses. Commonly employed in the preparation of protease inhibitors and other bioactive molecules where stereochemistry plays a critical role in biological activity. The tosylate group acts as a leaving group, enabling nucleophilic substitution to introduce various side chains, while the benzyl carbamate (Cbz) group protects the nitrogen and can be removed under mild conditions without affecting other functional groups. Widely applied in medicinal chemistry for constructing complex nitrogen-containing heterocycles.
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