(R)-4-Benzyl-2-(6-methylpyridin-2-yl)-4,5-dihydrooxazole
97%, 99%e.e.
Reagent
Code: #231823
CAS Number
2757082-98-5
blur_circular Chemical Specifications
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Molecular Information
Weight
252.31 g/mol
Formula
C₁₆H₁₆N₂O
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Storage & Handling
Storage
2-8°C, Sealed, Dry, Light-proof, Inert Gas
description Product Description
Used as a chiral intermediate in the synthesis of biologically active compounds, particularly in the development of pharmaceuticals targeting central nervous system disorders. Its 4,5-dihydrooxazole (oxazoline) core, featuring a 6-methylpyridin-2-yl substituent, and stereogenic center make it valuable in asymmetric synthesis, where it helps control the stereochemistry of final drug molecules. Commonly employed in the preparation of enzyme inhibitors and receptor modulators due to its ability to mimic peptide bonds and enhance metabolic stability. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies, especially in optimizing lead compounds for improved potency and selectivity.
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