(3R,4R)-tert-Butyl 4-amino-3-fluoropiperidine-1-carboxylate

98%

Reagent Code: #231248
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CAS Number 1260612-08-5

science Other reagents with same CAS 1260612-08-5

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scatter_plot Molecular Information
Weight 218.27 g/mol
Formula C₁₀H₁₉FN₂O₂
badge Registry Numbers
MDL Number MFCD12756122
inventory_2 Storage & Handling
Storage 2-8°C, drying away from light

description Product Description

Widely used as a key chiral intermediate in the synthesis of pharmaceutical agents, particularly in the development of protease inhibitors and antiviral drugs. Its fluorinated piperidine structure enhances metabolic stability and bioavailability, making it valuable in optimizing drug candidates. Commonly employed in the preparation of hepatitis C virus (HCV) NS3/4A protease inhibitors due to its ability to mimic peptide motifs while resisting enzymatic degradation. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies, where the amine and fluorine functionalities allow for selective derivatization and improved target binding.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿2,560.00
inventory 1g
10-20 days ฿9,600.00
inventory 5g
10-20 days ฿25,600.00

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(3R,4R)-tert-Butyl 4-amino-3-fluoropiperidine-1-carboxylate
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Widely used as a key chiral intermediate in the synthesis of pharmaceutical agents, particularly in the development of protease inhibitors and antiviral drugs. Its fluorinated piperidine structure enhances metabolic stability and bioavailability, making it valuable in optimizing drug candidates. Commonly employed in the preparation of hepatitis C virus (HCV) NS3/4A protease inhibitors due to its ability to mimic peptide motifs while resisting enzymatic degradation. Also utilized in medicinal chemistry fo

Widely used as a key chiral intermediate in the synthesis of pharmaceutical agents, particularly in the development of protease inhibitors and antiviral drugs. Its fluorinated piperidine structure enhances metabolic stability and bioavailability, making it valuable in optimizing drug candidates. Commonly employed in the preparation of hepatitis C virus (HCV) NS3/4A protease inhibitors due to its ability to mimic peptide motifs while resisting enzymatic degradation. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies, where the amine and fluorine functionalities allow for selective derivatization and improved target binding.

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