(3R,4R)-tert-Butyl 4-amino-3-fluoropiperidine-1-carboxylate
98%
science Other reagents with same CAS 1260612-08-5
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description Product Description
Widely used as a key chiral intermediate in the synthesis of pharmaceutical agents, particularly in the development of protease inhibitors and antiviral drugs. Its fluorinated piperidine structure enhances metabolic stability and bioavailability, making it valuable in optimizing drug candidates. Commonly employed in the preparation of hepatitis C virus (HCV) NS3/4A protease inhibitors due to its ability to mimic peptide motifs while resisting enzymatic degradation. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies, where the amine and fluorine functionalities allow for selective derivatization and improved target binding.
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