2-(2-Pyrimidinyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
95%
Reagent
Code: #226814
CAS Number
1597008-13-3
blur_circular Chemical Specifications
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Molecular Information
Weight
213.2 g/mol
Formula
C₁₁H₁₁N₅
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Storage & Handling
Storage
2-8°C, dry, closed
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly for targeting protein kinases involved in inflammatory diseases and cancer. It serves as a scaffold in developing selective inhibitors due to its ability to mimic purine bases, allowing effective binding to ATP-binding sites in enzymes. Also explored in the design of central nervous system agents owing to its capacity to cross the blood-brain barrier. Its tetrahydropyrido ring enhances solubility and metabolic stability, making it favorable for oral drug formulations.
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