2-(2-Pyrimidinyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
95%
science Other reagents with same CAS 1597008-13-3
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description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly for targeting protein kinases involved in inflammatory diseases and cancer. It serves as a scaffold in developing selective inhibitors due to its ability to mimic purine bases, allowing effective binding to ATP-binding sites in enzymes. Also explored in the design of central nervous system agents owing to its capacity to cross the blood-brain barrier. Its tetrahydropyrido ring enhances solubility and metabolic stability, making it favorable for oral drug formulations.
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