N-Boc-Piperidine-4-carboxylic acid methyl ester
98%
Reagent
Code: #217003
Alias
1-Boc-4-piperidinic acid methyl ester; 1-tert-butyl 4-methyl ester-1,4-dicarboxylate
CAS Number
124443-68-1
science Other reagents with same CAS 124443-68-1
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Molecular Information
Weight
243.30 g/mol
Formula
C₁₂H₂₁NO₄
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Registry Numbers
MDL Number
MFCD02183584
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Storage & Handling
Storage
Room temperature, sealed
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) where protection of the piperidine nitrogen is required. The Boc (tert-butoxycarbonyl) group allows for selective protection during peptide coupling or heterocyclic assembly, while the methyl ester offers a handle for hydrolysis or nucleophilic substitution. Commonly employed in medicinal chemistry for constructing kinase inhibitors, CNS agents, and other bioactive molecules containing substituted piperidine scaffolds. Its stability under various reaction conditions makes it suitable for multi-step synthetic sequences.
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