N-Boc-piperidine-3-methanol
98%
Reagent
Code: #216611
Alias
N-Boc-3-piperidinyl methanol
CAS Number
116574-71-1
blur_circular Chemical Specifications
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Molecular Information
Weight
215.29 g/mol
Formula
C₁₁H₂₁NO₃
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Registry Numbers
MDL Number
MFCD03094733
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Physical Properties
Melting Point
77-81°C
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Storage & Handling
Storage
Room temperature
description Product Description
Widely used in pharmaceutical synthesis, this compound serves as a key intermediate in the preparation of active pharmaceutical ingredients (APIs), particularly those involving piperidine-based structures. Its Boc-protected amine group allows for selective reactivity, making it valuable in multi-step organic syntheses where controlled deprotection and functionalization are required. The primary alcohol group can be easily modified through esterification, ether formation, or oxidation, enabling incorporation into more complex molecular architectures. It is especially useful in the development of central nervous system agents, including analgesics and neuromodulators, due to the prevalence of functionalized piperidine rings in bioactive molecules. Additionally, it is employed in combinatorial chemistry and medicinal chemistry research for building diverse compound libraries.
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