Used as a key intermediate in the synthesis of complex nitrogen-containing pharmaceuticals, particularly in the development of neuroactive agents and central nervous system modulators. Its rigid tricyclic structure and defined stereochemistry make it valuable for constructing selective ligands targeting neurotransmitter receptors. The nitro group allows further functionalization, enabling the introduction of amine or other pharmacophoric elements. The tert-butoxycarbonyl (Boc) protecting group ensures compatibility in multi-step peptide-like syntheses, providing controlled deprotection under mild acidic conditions. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its ability to lock conformations and enhance metabolic stability in drug candidates.