5-Iodo-2-(piperidin-3-yl)-1,2,3,4-tetrahydroisoquinolinehydrochloride
97%
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Used in pharmaceutical research as a key intermediate for synthesizing compounds targeting central nervous system disorders. Shows potential in the development of neuroprotective agents and treatments for neurodegenerative diseases like Parkinson’s and Alzheimer’s. Also explored for its role in serotonin and dopamine receptor modulation, making it relevant in studying antidepressant and antipsychotic therapies. Commonly employed in structure-activity relationship (SAR) studies to optimize drug candidates for improved brain penetration and receptor selectivity. Additionally, due to the iodine substituent, it serves as a precursor for radiolabeled analogs using I-125 or I-131, employed as standards or ligands in biochemical assays to study receptor-ligand interactions at the cellular level.
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