6-Iodo-7-methoxyquinazolin-4(3H)-one
95%
Reagent
Code: #201058
CAS Number
206190-25-2
blur_circular Chemical Specifications
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Molecular Information
Weight
302.07 g/mol
Formula
C₉H₇IN₂O₂
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Registry Numbers
MDL Number
MFCD27756712
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Storage & Handling
Storage
2-8°C, sealed, dry, light-proof
description Product Description
Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in the development of anticancer agents. Its structure allows for selective modification at the 6 and 7 positions, enabling the creation of targeted therapies that inhibit epidermal growth factor receptor (EGFR) signaling. Commonly employed in research settings to develop small molecule drugs for treating non-small cell lung cancer and other EGFR-driven tumors. Also utilized in radiolabeling studies due to the presence of iodine, facilitating imaging and biodistribution analysis in preclinical models.
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