8-iodo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
≥95%
Reagent
Code: #199539
CAS Number
1245648-97-8
blur_circular Chemical Specifications
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Molecular Information
Weight
260.04 g/mol
Formula
C₆H₅IN₄
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Registry Numbers
MDL Number
MFCD18072718
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Storage & Handling
Storage
Room temperature, light-proof, inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its iodo-substituted triazolopyridine structure facilitates selective binding to enzyme targets and is valuable in medicinal chemistry research. Commonly employed in the preparation of bioactive molecules through cross-coupling reactions, especially palladium-catalyzed transformations like Suzuki or Sonogashira couplings. The core scaffold also shows potential in designing central nervous system agents due to interactions with neurotransmitter systems, though primary applications focus on oncology and anti-inflammatory targets.
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