3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-5,8-difluoro-4(1H)-quinolinone
≥90%
Reagent
Code: #197803
CAS Number
478033-69-1
blur_circular Chemical Specifications
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Molecular Information
Weight
360.67 g/mol
Formula
C₁₅H₆ClF₅N₂O
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Registry Numbers
MDL Number
MFCD02082505
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Storage & Handling
Storage
2-8°C, sealed, dry, light-proof
description Product Description
Used as a key intermediate in the synthesis of potent kinase inhibitors, particularly in the development of anticancer agents. Its structure enables selective binding to ATP sites in protein kinases, making it valuable in targeting signaling pathways involved in tumor growth and proliferation. It has shown promise in research focused on treating solid tumors and hematological malignancies. Additionally, its fluorinated and chlorinated moieties enhance metabolic stability and bioavailability, which are critical for oral drug formulations. Widely utilized in medicinal chemistry for structure-activity relationship (SAR) studies to optimize potency and selectivity in drug candidates.
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