5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
≥95%
Reagent
Code: #193922
CAS Number
862723-42-0
blur_circular Chemical Specifications
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Molecular Information
Weight
244.10 g/mol
Formula
C₁₃H₁₇BN₂O₂
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Registry Numbers
MDL Number
MFCD07367523
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Physical Properties
Boiling Point
404.1±18.0 °C(Predicted)
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Storage & Handling
Density
1.15±0.1 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of pharmaceuticals and biologically active molecules. Its indazole core is commonly found in kinase inhibitors and other therapeutic agents, making it valuable in drug discovery. The boronate ester group allows for efficient and selective coupling with aryl or heteroaryl halides under mild palladium catalysis. It is especially useful in constructing complex heterocyclic systems for research in oncology, inflammation, and central nervous system disorders. Commonly employed in medicinal chemistry for lead optimization and library synthesis.
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