3-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
95%
Reagent
Code: #193810
Alias
tert-butyl 3-hydroxymethylpiperazine-1-carboxylate
CAS Number
301673-16-5
science Other reagents with same CAS 301673-16-5
blur_circular Chemical Specifications
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Molecular Information
Weight
216.28 g/mol
Formula
C₁₀H₂₀N₂O₃
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Registry Numbers
MDL Number
MFCD04115304
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of active pharmaceutical ingredients (APIs) that require piperazine moieties. Its protected functional groups allow selective reactions in multi-step organic syntheses, especially in the production of kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs. The tert-butyl carbamate (Boc) group provides stability during reactions and can be easily removed under mild acidic conditions, making it ideal for solid-phase and solution-phase peptide-like synthesis. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its ability to modulate solubility, bioavailability, and binding affinity.
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