6-Methyl-2-(((3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole
98%
Reagent
Code: #192723
CAS Number
1182733-62-5
science Other reagents with same CAS 1182733-62-5
blur_circular Chemical Specifications
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Molecular Information
Weight
367.39 g/mol
Formula
C₁₇H₁₆F₃N₃OS
thermostat
Physical Properties
Melting Point
156-158 °C
Boiling Point
507.3±60.0 °C(Predicted)
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Storage & Handling
Density
1.38±0.1 g/cm3(Predicted)
Storage
Room temperature, seal, inert gas
description Product Description
Used as an intermediate in the synthesis of proton pump inhibitors (PPIs), particularly in the production of tenatoprazole and related compounds. It plays a key role in developing drugs that reduce gastric acid secretion, making it valuable in treating acid-related gastrointestinal disorders such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. Its structure allows for enhanced stability and prolonged inhibition of the H+/K+-ATPase enzyme in the stomach lining, contributing to longer-lasting therapeutic effects compared to earlier PPIs. Commonly employed in research and development for next-generation acid suppressants with improved pharmacokinetic profiles.
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