(1-Ethyl-1H-indazol-5-yl)boronic acid
95%
Reagent
Code: #183511
CAS Number
952319-70-9
blur_circular Chemical Specifications
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Molecular Information
Weight
190.01 g/mol
Formula
C₉H₁₁BN₂O₂
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Registry Numbers
MDL Number
MFCD22576144
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Physical Properties
Boiling Point
399.8±34.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, stored in inert gas
description Product Description
Used primarily as a key intermediate in the synthesis of pharmaceutical compounds, especially in the development of kinase inhibitors for cancer treatment. Its boronic acid functional group enables participation in Suzuki-Miyaura cross-coupling reactions, making it valuable in constructing biaryl frameworks found in bioactive molecules. Commonly employed in medicinal chemistry for lead optimization due to its ability to enhance binding affinity and metabolic stability. Also utilized in the preparation of analogs for structure-activity relationship (SAR) studies in drug discovery programs targeting inflammatory and oncological diseases.
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