Ethyl 6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate
95%
Reagent
Code: #182568
CAS Number
79660-46-1
science Other reagents with same CAS 79660-46-1
blur_circular Chemical Specifications
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Molecular Information
Weight
271.19 g/mol
Formula
C₁₂H₈F₃NO₃
thermostat
Physical Properties
Melting Point
275°C
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of fluoroquinolone antibiotics, particularly in the production of advanced antimicrobial agents. Its structure allows for further functionalization at the 1-position and 7-position of the quinoline core, enabling the development of compounds with enhanced activity against resistant bacterial strains. Commonly employed in pharmaceutical research to build quinolone-based drugs targeting DNA gyrase and topoisomerase IV. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies to optimize potency, spectrum of activity, and pharmacokinetic properties.
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