Ethyl 6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate

95%

Reagent Code: #182568
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CAS Number 79660-46-1

science Other reagents with same CAS 79660-46-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 271.19 g/mol
Formula C₁₂H₈F₃NO₃
thermostat Physical Properties
Melting Point 275°C
inventory_2 Storage & Handling
Storage Room temperature, dry

description Product Description

Used as a key intermediate in the synthesis of fluoroquinolone antibiotics, particularly in the production of advanced antimicrobial agents. Its structure allows for further functionalization at the 1-position and 7-position of the quinoline core, enabling the development of compounds with enhanced activity against resistant bacterial strains. Commonly employed in pharmaceutical research to build quinolone-based drugs targeting DNA gyrase and topoisomerase IV. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies to optimize potency, spectrum of activity, and pharmacokinetic properties.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿630.00
inventory 5g
10-20 days ฿1,470.00

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Ethyl 6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate
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Used as a key intermediate in the synthesis of fluoroquinolone antibiotics, particularly in the production of advanced antimicrobial agents. Its structure allows for further functionalization at the 1-position and 7-position of the quinoline core, enabling the development of compounds with enhanced activity against resistant bacterial strains. Commonly employed in pharmaceutical research to build quinolone-based drugs targeting DNA gyrase and topoisomerase IV. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies to optimize potency, spectrum of activity, and pharmacokinetic properties.
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