Used in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its alkyne functionality allows it to participate in click chemistry reactions, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC), making it valuable in drug discovery for building molecular complexity. The pyrimidine core is a common motif in bioactive molecules, enabling the compound to serve as a building block for kinase inhibitors and other therapeutic agents. It is also employed in materials science for constructing functionalized heterocyclic systems used in electronic and optical devices.