6,8-Difluoroquinoline-3-carbonitrile
95%
Reagent
Code: #177462
CAS Number
71083-55-1
science Other reagents with same CAS 71083-55-1
blur_circular Chemical Specifications
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Molecular Information
Weight
190.15 g/mol
Formula
C₁₀H₄F₂N₂
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Registry Numbers
MDL Number
MFCD27927783
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Physical Properties
Boiling Point
322.8±37.0 °C(Predicted)
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Storage & Handling
Density
1.39±0.1 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of fluorinated quinoline-based pharmaceuticals, particularly in the development of antimalarial and anticancer agents. Its structure supports the construction of complex heterocyclic systems that enhance drug potency and metabolic stability. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the electron-withdrawing nitrile and fluorine substituents, which influence binding affinity and bioavailability. Also utilized in the preparation of kinase inhibitors and antimicrobial compounds.
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