6,8-Difluoroquinoline-3-carbonitrile

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Reagent Code: #177462
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CAS Number 71083-55-1

science Other reagents with same CAS 71083-55-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 190.15 g/mol
Formula C₁₀H₄F₂N₂
badge Registry Numbers
MDL Number MFCD27927783
thermostat Physical Properties
Boiling Point 322.8±37.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.39±0.1 g/cm3(Predicted)
Storage 2-8°C

description Product Description

Used as a key intermediate in the synthesis of fluorinated quinoline-based pharmaceuticals, particularly in the development of antimalarial and anticancer agents. Its structure supports the construction of complex heterocyclic systems that enhance drug potency and metabolic stability. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the electron-withdrawing nitrile and fluorine substituents, which influence binding affinity and bioavailability. Also utilized in the preparation of kinase inhibitors and antimicrobial compounds.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿4,740.00
inventory 250mg
10-20 days ฿9,110.00
inventory 1g
10-20 days ฿18,210.00

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6,8-Difluoroquinoline-3-carbonitrile
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Used as a key intermediate in the synthesis of fluorinated quinoline-based pharmaceuticals, particularly in the development of antimalarial and anticancer agents. Its structure supports the construction of complex heterocyclic systems that enhance drug potency and metabolic stability. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the electron-withdrawing nitrile and fluorine substituents, which influence binding affinity and bioavailability. Also utilized in the preparation of kinase inhibitors and antimicrobial compounds.
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