2-Aminopyrrolo[2,1-f][1,2,4]triazin-4(3H)-one
≥95%
Reagent
Code: #173612
CAS Number
159326-75-7
blur_circular Chemical Specifications
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Molecular Information
Weight
150.14 g/mol
Formula
C₆H₆N₄O
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Registry Numbers
MDL Number
MFCD21364507
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used in pharmaceutical research as a key scaffold in the development of kinase inhibitors, particularly for targeting cancer-related enzymes such as EGFR and Aurora kinases. Its structure supports high binding affinity to ATP sites in kinases, making it valuable in designing small-molecule therapeutics. Also explored in medicinal chemistry for antiviral and anti-inflammatory drug candidates due to its ability to modulate biological pathways. Commonly functionalized at the 2-amino group to enhance solubility, selectivity, and metabolic stability in drug leads.
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