3´-Chloro-5´-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2´]bipyridinyl-3-ylaminehydrochloride
97%
Reagent
Code: #164376
CAS Number
1185313-62-5
blur_circular Chemical Specifications
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Molecular Information
Weight
316.15 g/mol
Formula
C₁₁H₁₄Cl₂F₃N₃
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Registry Numbers
MDL Number
MFCD09877740
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of selective kinase inhibitors, particularly those targeting neurodegenerative diseases and certain cancers. Its structure supports blood-brain barrier penetration, making it valuable in developing central nervous system (CNS) therapeutics. Also employed in the optimization of drug candidates requiring enhanced metabolic stability and binding affinity due to the presence of trifluoromethyl and chloro substituents. Commonly utilized in structure-activity relationship (SAR) studies to improve potency and selectivity.
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