3-(4-Chloro-pyrimidin-2-yl)-1H-indole
97%
Reagent
Code: #164319
CAS Number
1146080-35-4
blur_circular Chemical Specifications
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Molecular Information
Weight
229.67 g/mol
Formula
C₁₂H₈ClN₃
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Registry Numbers
MDL Number
MFCD11915918
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Physical Properties
Boiling Point
340.4±34.0 °C(Predicted)
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Storage & Handling
Density
1.387 g/cm3
Storage
Room temperature, seal, dry
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly for targeting protein kinases involved in cancer and inflammatory diseases. Its structure enables selective binding to enzyme active sites, making it valuable in developing targeted therapies. Also explored in agrochemicals for designing novel pesticides due to its ability to modulate biological activity in pest organisms. Commonly employed in structure-activity relationship (SAR) studies to optimize drug candidates for improved potency and metabolic stability.
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