1-(5-Chloropyrimidin-2-yl)azetidine-3-carboxylic acid

95%

Reagent Code: #163376
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CAS Number 1289386-16-8

science Other reagents with same CAS 1289386-16-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 213.62 g/mol
Formula C₈H₈ClN₃O₂
badge Registry Numbers
MDL Number MFCD18837467
inventory_2 Storage & Handling
Storage 2-8°C, sealed, dry

description Product Description

Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors for targeted cancer therapies. Its structure enables selective binding to enzyme active sites, making it valuable in drug discovery programs focused on oncology and inflammatory diseases. The compound's azetidine and chloropyrimidine moieties contribute to metabolic stability and improved pharmacokinetic profiles in final drug candidates. It is also employed in the preparation of covalent inhibitors due to the reactivity of the chlorine atom, allowing for irreversible target engagement. Commonly utilized in medicinal chemistry research for structure-activity relationship (SAR) studies to optimize potency and selectivity.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿8,260.00

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1-(5-Chloropyrimidin-2-yl)azetidine-3-carboxylic acid
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Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors for targeted cancer therapies. Its structure enables selective binding to enzyme active sites, making it valuable in drug discovery programs focused on oncology and inflammatory diseases. The compound's azetidine and chloropyrimidine moieties contribute to metabolic stability and improved pharmacokinetic profiles in final drug candidates. It is also employed in the preparation of covalent inhibitors due to the reactivity of the chlorine atom, allowing for irreversible target engagement. Commonly utilized in medicinal chemistry research for structure-activity relationship (SAR) studies to optimize potency and selectivity.
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