4-Chloro-2-(6-chloro-4-oxo-1,4-dihydroquinazolin-2-yl)phenyl dihydrogen phosphate
95%
science Other reagents with same CAS 147394-94-3
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description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly those targeting epidermal growth factor receptor (EGFR) pathways. Its structure supports the development of anticancer agents by enabling selective inhibition of kinase activity involved in tumor growth and progression. Commonly employed in the preparation of active pharmaceutical ingredients (APIs) for targeted cancer therapies, especially in non-small cell lung cancer (NSCLC) treatment. Also utilized in structure-activity relationship (SAR) studies to optimize potency, selectivity, and metabolic stability of kinase inhibitor candidates.
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