3-Bromo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine
95%
Reagent
Code: #154418
CAS Number
918525-02-7
blur_circular Chemical Specifications
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Molecular Information
Weight
353.37 g/mol
Formula
C₁₆H₂₅BrN₂Si
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Registry Numbers
MDL Number
MFCD15529606
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Storage & Handling
Storage
-20°C, Sealed, Dry, Lightproof, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows selective functionalization in cross-coupling reactions, making it valuable in constructing complex heterocyclic systems found in bioactive molecules. Commonly employed in palladium-catalyzed reactions such as Suzuki or Negishi couplings to form carbon-carbon bonds in drug discovery pipelines. The silyl protecting group enhances stability and regioselectivity during multi-step syntheses.
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