5-Bromo-4-Fluoro-1-(Triisopropylsilyl)-1H-Pyrrolo[2,3-B]Pyridine
97%
Reagent
Code: #153965
CAS Number
685513-91-1
blur_circular Chemical Specifications
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Molecular Information
Weight
371.36 g/mol
Formula
C₁₆H₂₄BrFN₂Si
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its protected pyrrolopyridine core allows selective functionalization during multi-step reactions, making it valuable in medicinal chemistry for constructing complex drug candidates. The silyl protecting group enhances stability and solubility in organic solvents, facilitating purification and handling during synthesis. Commonly employed in cross-coupling reactions such as Suzuki or Negishi to introduce aryl or heteroaryl groups, enabling the exploration of structure-activity relationships in drug discovery programs.
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