tert-Butyl 2-oxo-7-azabicyclo[2.2.1]heptane-7-carboxylate
97%
Reagent
Code: #146261
CAS Number
152533-47-6
science Other reagents with same CAS 152533-47-6
blur_circular Chemical Specifications
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Molecular Information
Weight
211.26 g/mol
Formula
C₁₁H₁₇NO₃
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Registry Numbers
MDL Number
MFCD18633018
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of neuroactive compounds, nootropic agents, antivirals, and specific enzyme inhibitors. Its rigid bicyclic 7-azabicyclo[2.2.1]heptane structure, with the tert-butyl carboxylate protecting group at the nitrogen, enables precise control of reactions at other sites during synthesis, enhancing metabolic stability and blood-brain barrier penetration in peptide-like modifications. The protecting group can be easily removed in later steps, making it ideal for structure-activity relationship (SAR) studies targeting central nervous system disorders and for preparing conformationally constrained enzyme inhibitors with improved binding affinity and selectivity.
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