α-MaleiMidopropionyl-ω-succiniMidyl-8(ethylene glycol)
95%
Reagent
Code: #63581
CAS Number
756525-93-6
blur_circular Chemical Specifications
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Molecular Information
Weight
689.71 g/mol
Formula
C₃₀H₄₇N₃O₁₆
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Registry Numbers
MDL Number
MFCD11041144
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Storage & Handling
Storage
2-8°C
description Product Description
Used in bioconjugation, this chemical serves as a linker for attaching biomolecules, such as proteins or peptides, to other entities like nanoparticles or polymers. Its maleimide group reacts with thiols, enabling stable bonds with cysteine residues in proteins, while the succinimidyl ester reacts with primary amines, allowing conjugation with lysine residues or amine-containing molecules. The ethylene glycol segment enhances solubility and reduces nonspecific interactions, making it suitable for applications in drug delivery, diagnostics, and targeted therapy. It is particularly useful in creating antibody-drug conjugates (ADCs) or functionalizing surfaces for biosensors.
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