7-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)heptanoic acid

95%

Reagent Code: #50086
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CAS Number 90267-85-9

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scatter_plot Molecular Information
Weight 225.2411 g/mol
Formula C₁₁H₁₅NO₄
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MDL Number MFCD00941277
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Storage room temperature

description Product Description

7-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)heptanoic acid is a heterobifunctional linker featuring a maleimide group and a carboxylic acid terminus. It is primarily used in bioconjugation chemistry, where the maleimide selectively reacts with thiol groups (e.g., cysteine residues) via Michael addition, enabling the attachment of biomolecules, drugs, or labels to proteins, antibodies, and nanoparticles. The carboxylic acid can be activated (e.g., with EDC/NHS) for coupling to amine groups, facilitating applications in targeted drug delivery, immunotherapy, and diagnostic assays. In polymer science, it serves as a crosslinker for thiol-containing polymers, enhancing network formation in hydrogels, biocompatible coatings, and surface modifications for biomedical devices.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿3,924.00

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