Cyclohexanone O-((6-((((cyclohexylideneamino)oxy)carbonyl)amino)hexyl)carbamoyl) oxime
10mM in DMSO
Reagent
Code: #157923
CAS Number
83654-05-1
blur_circular Chemical Specifications
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Molecular Information
Weight
394.51 g/mol
Formula
C₂₀H₃₄N₄O₄
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Registry Numbers
MDL Number
MFCD00210844
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Storage & Handling
Storage
-20°C
description Product Description
Used as a bifunctional crosslinking agent in bioconjugation, particularly in the development of antibody-drug conjugates (ADCs) and protein labeling. The compound enables selective coupling between biomolecules and functional payloads through its dual reactive oxime groups. One end selectively reacts with ketone or aldehyde groups on glycoproteins, while the other end participates in amide or carbamate formation with amines, allowing stable linkage formation under mild conditions. It is especially valuable in pharmaceutical research for constructing targeted therapeutics where controlled linkage stability and specificity are critical. Its cyclohexyl and hexyl spacers provide favorable solubility and reduce steric hindrance, enhancing conjugation efficiency.
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