Pyraflufen is a highly effective herbicide used primarily in post-emergence control of broadleaf weeds in cereal crops such as wheat and barley. It works by inhibiting protoporphyrinogen oxidase (PPO), an enzyme critical in chlorophyll synthesis, leading to the accumulation of toxic compounds in plant cells and rapid desiccation of green tissues under sunlight. It is valued for its fast action, with visible weed control within hours of application, and its low use rate, making it cost-effective and reducing environmental load. Pyraflufen is often combined with other herbicides to broaden the spectrum of weed control and to manage herbicide-resistant weed populations. Due to its foliar activity and quick degradation in soil, it has minimal residual effect, allowing for flexible crop rotation. It is especially useful against difficult-to-control weeds like chickweed, shepherd’s purse, and mayweed. Its selectivity in cereal crops ensures crop safety when applied at recommended growth stages.