Pyroxasulfone is a herbicide used primarily in pre-emergent weed control in crops such as corn, soybeans, and cotton. It effectively controls a broad spectrum of annual grasses and certain broadleaf weeds by inhibiting very-long-chain fatty acid synthesis, which is essential for cell membrane formation in susceptible plants. Due to its soil residual activity, it provides extended weed control early in the growing season, reducing the need for multiple herbicide applications. It is often used in combination with other herbicides to enhance spectrum and manage resistance. Its low use rate and favorable environmental profile make it suitable for integrated weed management programs in conservation tillage systems.